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Entries for 'Administrator Account'
Administrator Account posted on December 06, 2014 13:51
Abstract. The therapeutic efficiency and safety of the proteolytic enzyme bromelaine obtained from pineapple (Bromelain-POS®,Ursapharm GmbH, Saarbrücken, Germany) was evaluated in children under the age of 11 years diagnosed with acute sinusitis. Data from 116 patients from 19 centres located across Germany were analysed in a pharmacoepidemiological cohort study. Patient cohorts wereeither treated with Bromelain-POS® (N=62), in combination with Bromelain-POS® and standard therapies (N=34), or with standard therapies(N=20). The primary parameter measuring effectiveness of the different treatment groups was the duration of symptoms. The shortest mean period of symptoms was observed in patients treated with Bromelain-POS® alone (6.66 days), followed by the standard therapy (7.95 days)and those treated with a combination of Bromelain-POS® and the standard therapy (9.06 days). Patients of the Bromelain-POS®monotherapy group showed a statistically significant faster recovery from symptoms (p=0.005) compared to the other treatment groups. One10-year-old male patient, with a known pineapple allergy, showed a self-limiting mild allergic reaction. No other unwanted side- effects were reported. This trial documents that the proteolytic pineapple enzyme Bromelain-POS® is widely used in the treatment of young childrendiagnosed with acute sinusitis in Germany and that the use of proteolytic enzymes can benefit such patients.
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Administrator Account posted on October 19, 2014 14:28
Bromelain can be considered an effective therapeutic
option for PLC; its efficacy could be related to its anti-inflammatory,
immunomodulatory and/or anti-viral properties.
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Administrator Account posted on October 08, 2014 15:29
Bromelain is a mixture of enzymes that digest protein (proteolytic) that are found in pineapples (Ananas comosus). Pineapple has been used for centuries in Central and South America to treat indigestion and reduce inflammation. Bromelain, which is derived from the stem and juice of the pineapple, was first isolated from the pineapple plant in the late 1800s. The German Commission E approved bromelain to treat swelling and inflammation after surgery, particularly sinus surgery.
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